优德亚洲平台

Recombinant Human Secreted and transmembrane protein 1(SECTM1),partial

In Stock
  • 货号:
    CSB-MP819898HU
  • 规格:
  • 图片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Activity
      Measured by its binding ability in a functional ELISA. Immobilized CD7 (CSB-MP004953HU) at 5 μg/ml can bind human SECTM1, the EC50 is 1.811-3.372 ng/ml. Biological Activity Assay
  • 其他:

优德亚洲平台

  • 纯度:
    Greater than 85% as determined by SDS-PAGE.
  • 内毒素:
    Less than 1.0 EU/ug as determined by LAL method.
  • 生物活性:
    ①Measured by its binding ability in a functional ELISA. Immobilized CD7 (CSB-MP004953HU) at 5 μg/ml can bind human SECTM1, the EC50 is 1.811-3.372 ng/ml.
  • 基因名:
    SECTM1
  • Uniprot No.:
  • 别名:
    (Protein K-12)(K12)
  • 分子结构:
  • 种属:
    Homo sapiens (Human)
  • 【优德线上娱乐场】蛋白长度:
    Partial
  • 来源:
    Mammalian cell
  • 分子量:
    41.6 kDa
  • 表达区域:
    29-145aa
  • 氨基酸序列
    QNEGWDSPICTEGVVSVSWGENTVMSCNISNAFSHVNIKLRAHGQESAIFNEVAPGYFSRDGWQLQVQGGVAQLVIKGARDSHAGLYMWHLVGHQRNNRQVTLEVSGAEPQSAPDTG
  • 【优德线上娱乐场】蛋白标签:
    C-terminal hFc-tagged
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液:
    Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • 产品描述:
    May be involved in thymocyte signaling.
  • Datasheet & COA:
    Please contact us to get it.

靶点详情

  • 功能:
    May be involved in thymocyte signaling.
  • 基因功能参考文献:
    1. CD7 is present on monocytes and tumor macrophages and its ligand, SECTM1, is frequently expressed in corresponding melanoma tissues PMID: 24157461
    2. SECTM1 secreted from bone marrow stromal cells may interact with CD7 to influence GM-CSF expression in leukemic cells. PMID: 24211252
    3. level of SECTM1 expression is likely to be a key factor in innate immune responses and in the immune tolerance of cancerous cells PMID: 21749909
  • 亚细胞定位:
    Cell membrane, Single-pass type I membrane protein, Secreted
  • 【优德线上娱乐场】蛋白家族:
    SECTM family
  • 组织特异性:
    Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic
  • 数据库链接:

    HGNC: 10707

    OMIM: 602602

    KEGG: hsa:6398

    STRING: 9606.ENSP00000269389

    UniGene: Hs.558009



千赢国际qy88.vⅰp+qy88.vipmanbetxapp优德亚洲平台beplay3下载